Bis-dPEG21-NHS ester - Names and Identifiers
Bis-dPEG21-NHS ester - Physico-chemical Properties
| Molecular Formula | C54H96N2O29
|
| Molar Mass | 1237.34 |
| Storage Condition | 2-8°C，干燥，密封 |
| MDL | MFCD21363289 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Bis-dPEG21-NHS ester - Reference Information
| biological activity | Bis-PEG21-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Bis-PEG21-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG21-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | PEGs Alkyl/ether Cleavable |
| in vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 01:59:58
